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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL221730
Molecular formula	C27H26ClFN2O3S
IUPAC name	5-[[4-[1-[(5-chlorothiophen-2-yl)methyl]-6-fluoroindol-3-yl]piperidin-1-yl]methyl]-2-methoxybenzoic acid
Molecular weight	513.024
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.7
Synonyms	BDBM50156874 SCHEMBL5351387 5-{4-[1-(5-chlorothiophen-2-ylmethyl)-6-fluoro-1H-indol-3-yl]piperidin-1-ylmethyl}-2-methoxybenzoic acid
Inchi Key	KQSXGBBQVLGKRD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H26ClFN2O3S/c1-34-25-6-2-17(12-22(25)27(32)33)14-30-10-8-18(9-11-30)23-16-31(15-20-4-7-26(28)35-20)24-13-19(29)3-5-21(23)24/h2-7,12-13,16,18H,8-11,14-15H2,1H3,(H,32,33)
PubChem CID	10279311
ChEMBL	CHEMBL221730
IUPHAR	N/A
BindingDB	50156874
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
175871	Histamine H1 receptor	P70174	Hrh1	Mus musculus (Mouse)	488
175872	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
175870	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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