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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	475150-69-7
Molecular formula	C27H35N3O2
IUPAC name	(2R)-1-benzyl-N-(3-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylpropyl)pyrrolidine-2-carboxamide
Molecular weight	433.596
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.3
Synonyms	(R)-N-(3-(3H-Spiro[isobenzofuran-1,4'-piperidin]-1'-yl)propyl)-1-benzylpyrrolidine-2-carboxamide AKOS027422649 BDBM50181392 QC-2645 (2R)-1-(phenylmethyl)-N-(3-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylpropyl)pyrrolidine-2-carboxamide 1-benzyl-N-[3-spiro[isobenzofuran-1(3H),4''-piperidine]-1-yl]propyl-D-prolineamide BAN-ORL-24 CHEMBL201945 (R)-N-(3-(3H-spiro[isobenzofuran-1,4''-piperidine]-1''-yl)propyl)-1-benzylpyrrolidine-2-carboxamide BCP9000378 GTPL7361 0NN BAN ORL 24 HCL C-24 ZINC13679981 (2R)-1-(Phenylmethyl)-N-[3-(spiro[isobenzofuran-1(3H),4'-piperidin]-1-yl)propyl-2-pyrrolidinecarboxamide Banyu Compound-24 compound 24 [PMID: 16451050] (R)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-1-benzylpyrrolidine-2-carboxamide ABP000130 BCPP000353 NCGC00387110-02 1-Benzyl-N-[3-(1'h,3h-Spiro[2-Benzofuran-1,4'-Piperidin]-1'-Yl)propyl]-D-Prolinamide BAN ORL 24HCL (2R)-1-Benzyl-N-(3-spiro[isobenzofuran-1(3H),4'-piperidin]-1'-ylpropyl)-2-pyrrolidinecarboxamide BCP02619 D02NSY [ Show all ]
Inchi Key	MAKMQGKJURAJEN-RUZDIDTESA-N
Inchi ID	InChI=1S/C27H35N3O2/c31-26(25-12-6-17-30(25)20-22-8-2-1-3-9-22)28-15-7-16-29-18-13-27(14-19-29)24-11-5-4-10-23(24)21-32-27/h1-5,8-11,25H,6-7,12-21H2,(H,28,31)/t25-/m1/s1
PubChem CID	10296561
ChEMBL	CHEMBL201945
IUPHAR	7361
BindingDB	50181392
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
200762	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
200763	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
200765	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
200761	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370
200764	Nociceptin receptor	P35377	Oprl1	Mus musculus (Mouse)	367

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