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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL222356
Molecular formula	C27H27FN2O4
IUPAC name	5-[[4-[6-fluoro-1-(furan-3-ylmethyl)indol-3-yl]piperidin-1-yl]methyl]-2-methoxybenzoic acid
Molecular weight	462.521
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.1
Synonyms	BDBM50156877 SCHEMBL5348129 5-[4-(6-fluoro-1-furan-3-ylmethyl-1H-indol-3-yl)piperidin-1-ylmethyl]-2-methoxybenzoic acid
Inchi Key	PLADVISFXRAPMA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H27FN2O4/c1-33-26-5-2-18(12-23(26)27(31)32)14-29-9-6-20(7-10-29)24-16-30(15-19-8-11-34-17-19)25-13-21(28)3-4-22(24)25/h2-5,8,11-13,16-17,20H,6-7,9-10,14-15H2,1H3,(H,31,32)
PubChem CID	10139591
ChEMBL	CHEMBL222356
IUPHAR	N/A
BindingDB	50156877
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
262396	Histamine H1 receptor	P70174	Hrh1	Mus musculus (Mouse)	488
262398	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
262397	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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