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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL255169
Molecular formula	C21H26ClN3O
IUPAC name	N-[3-chloro-4-(4-ethylpiperazin-1-yl)phenyl]-3-phenylpropanamide
Molecular weight	371.909
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.9
Synonyms	MCULE-1821787460 ZINC4840170 MolPort-002-301-553 AC1MGJ7Q N-[3-chloro-4-(4-ethylpiperazin-1-yl)phenyl]-3-phenylpropanamide BDBM50373834 [ Show all ]
Inchi Key	SDHOGIQMQNVNCK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H26ClN3O/c1-2-24-12-14-25(15-13-24)20-10-9-18(16-19(20)22)23-21(26)11-8-17-6-4-3-5-7-17/h3-7,9-10,16H,2,8,11-15H2,1H3,(H,23,26)
PubChem CID	2986945
ChEMBL	CHEMBL255169
IUPHAR	N/A
BindingDB	50373834
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
311515	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
311517	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
311516	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
311513	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478
311514	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531

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