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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	144625-67-2
Molecular formula	C19H26FN3O5S
IUPAC name	[1-[2-(methanesulfonamido)ethyl]piperidin-4-yl]methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate
Molecular weight	427.491
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	2.2
Synonyms	AJ-23649 D03KNI L006965 AX8232749 GR 125487 sulfamate salt ZINC598219 CHEMBL471233 GTPL248 (1-(2-(Methylsulfonamido)ethyl)piperidin-4-yl)-methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate AKOS016003161 GR 125487 RT-022631 1H-Indole-3-carboxylic acid, 5-fluoro-2-methoxy-, (1-(2-((methylsulfonyl)amino)ethyl)-4-piperidinyl)methyl ester BRD-K62594868-082-03-7 GR-125487 [1-(2-methanesulfonamidoethyl)piperidin-4-yl]methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate AC1N7TG5 CTK8B8456 KB-204991 (1-(2-(methylsulfonamido)ethyl)piperidin-4-yl)methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate ANW-60395 GR 125487 sulfamate SCHEMBL2940596 CCG-204668 GR125487 [1-[2-(methanesulfonamido)ethyl]piperidin-4-yl]methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate [ Show all ]
Inchi Key	SSPCCAYAIDNNJX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H26FN3O5S/c1-27-18-17(15-11-14(20)3-4-16(15)22-18)19(24)28-12-13-5-8-23(9-6-13)10-7-21-29(2,25)26/h3-4,11,13,21-22H,5-10,12H2,1-2H3
PubChem CID	4284721
ChEMBL	N/A
IUPHAR	248
BindingDB	85020
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554870	5-hydroxytryptamine receptor 4	P97288	Htr4	Mus musculus (Mouse)	388
554871	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
556767	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
556768	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406

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