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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3703198
Molecular formula	C34H39FN2O6
IUPAC name	1-[4-[3-[[4-(2-ethylbutyl)-4-hydroxypiperidine-1-carbonyl]amino]-5-(4-fluorophenoxy)phenoxy]phenyl]cyclopropane-1-carboxylic acid
Molecular weight	590.692
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	6.5
Synonyms	BDBM149706 SCHEMBL14839321 US8975409, Example 13
Inchi Key	UZPSRIVFHKJDOL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H39FN2O6/c1-3-23(4-2)22-33(41)15-17-37(18-16-33)32(40)36-26-19-29(21-30(20-26)43-28-11-7-25(35)8-12-28)42-27-9-5-24(6-10-27)34(13-14-34)31(38)39/h5-12,19-21,23,41H,3-4,13-18,22H2,1-2H3,(H,36,40)(H,38,39)
PubChem CID	89484778
ChEMBL	CHEMBL3703198
IUPHAR	N/A
BindingDB	149706
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
349607	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
462229	Sphingosine 1-phosphate receptor 2	P47752	S1pr2	Rattus norvegicus (Rat)	352

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