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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Ramatroban
Molecular formula	C21H21FN2O4S
IUPAC name	3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid
Molecular weight	416.467
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.9
Synonyms	MFCD00887606 PubChem9956 (3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic Acid SC-00487 3-(4-Fluorophenylsulfonamido)-1,2,3,4-tetrahydro-9-carbazole propanoic acid Tox21_112516_1 9H-Carbazole-9-propanoicacid, 3-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-, (3R)- AOB5536 Baynas DB13036 GTPL1910 NCGC00167519-01 Ramatroban (JAN/INN) (R)-3-[3-(4-Fluorophenylsulphonylamino)-1,2,3,4-tetrahydrocarbazol- 9-yl]propionic acid SR-01000883932 3R-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid ZINC3798772 AC-719 Bay u-3405 BDBM50161746 CTK0H6708 DSSTox_RID_81819 HY-B0745 LDXDSHIEDAPSSA-OAHLLOKOSA-N NCGC00167519-07 (+)-(3R)-3-(p-Fluorobenzenesulfonamido)-1,2,3,4-tetrahydrocarbazole-9-propionic acid RT-011424 SR-01000946208-1 649F855 [3H]baynas AKOS015966619 BAY-u 3405 CAS-116649-85-5 D0P8TX EN-137774 MLS006010637 (R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydrocarbazol-9-yl)propanoic acid SCHEMBL29030 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid UNII-P1ALI72U6C A8X Bay u 3405 Baynas (TN) CHEMBL361812 DSSTox_CID_26685 GTPL1911 NCGC00167519-02 Ramatroban [INN:BAN] 116649-85-5 SR-01000883932-1 3R-[[(4-FLUOROPHENYL)SULFONYL]AMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-PROPANOICACID [3H]Bay u 3405 AC1L3XGV BAY u3405 C-35509 D01128 DTXSID1046685 J-003466 LS-172326 P1ALI72U6C (+)-(3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid S-7973 3(r)-[[(4-fluoro-phenyl) sulfonyl]amino]-1,2,3,4-tetrahydro-9h-carbazole-9-propanoic acid Tox21_112516 9H-Carbazole-9-propanoic acid, 3-(((4-fluorophenyl)sulfonyl)amino)-1,2,3,4-tetrahydro-, (R)- [3H]ramatroban AN-1137 Bay-u-3405 CHEBI:32087 FT-0080313 MolPort-005-943-701 Ramatroban (BAY u3405) (R)-3-(3-(4-fluorophenylsulfonamido)-3,4-dihydro-1H-carbazol-9(2H)-yl)propanoic acid SMR002530322 3-[(R)-3-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-propionic acid X6873 ABP001095 Bay u 3406 BC228169 CS-2956 DSSTox_GSID_46685 HMS3648E21 KS-1310 NCGC00167519-04 Ramatroban, >=98% (HPLC), solid SR-01000946208 [3H]BAY u3405 AJ-45646 BAY u3405;BAY-u3405 C21H21FN2O4S D0GC5H EN 137774 [ Show all ]
Inchi Key	LDXDSHIEDAPSSA-OAHLLOKOSA-N
Inchi ID	InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1
PubChem CID	123879
ChEMBL	CHEMBL361812
IUPHAR	1911, 1910
BindingDB	50161746
DrugBank	DB13036
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
185041	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
185038	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
185037	Prostaglandin D2 receptor 2	Q9Y5Y4	PTGDR2	Homo sapiens (Human)	395
554198	Prostaglandin D2 receptor 2	Q9Z2J6	Ptgdr2	Mus musculus (Mouse)	382
554199	Prostaglandin D2 receptor 2	Q6XKD3	Ptgdr2	Rattus norvegicus (Rat)	403
185036	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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