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Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	SB 204741
Molecular formula	C14H14N4OS
IUPAC name	1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea
Molecular weight	286.353
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.4
Synonyms	CCG-204350 FT-0643481 Lopac-S-0693 N-(1-Methyl-1H-indo-5-yl)-N'-(3-methyl-5-isothiazolyl)urea NCGC00015923-04 PDSP1_001580 SB204741 ZB000747 1-(1-methyl-5-indolyl)-3-(3-methyl-5-isothiazolyl)urea AKOS024456556 BCP28144 CHEMBL323356 HMS3260D12 MFCD00923644 N-(1-METHYL-1H-INDOLYL-5-YL)-N''-(3-METHYL-5-ISOTHIAZOLYL)UREA NCGC00025129-01 S 0693 SR-01000075765 C-18040 DTXSID80390956 KB-298203 N-(1-Methyl-1H-5-indolyl)-N inverted exclamation marka-(3-methyl-5-isothiazolyl)urea NCGC00015923-02 NCGC00260940-01 SB-204,741 Tocris-1372 1-(1-methyl-1H-indol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea A809277 API0007588 CHEBI:140936 GTPL221 Lopac0_000255 N-(1-Methyl-1H-indol-5-yl)-N'-(3-methyl-5-isothiazolyl)urea NCGC00015923-05 PDSP2_001564 SCHEMBL3377716 ZINC16912 1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea BDBM84991 CTK8F0087 HMS3369K08 MLS000862184 N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea NCGC00025129-02 SR-01000075765-1 3-(3-METHYL-1,2-THIAZOL-5-YL)-1-(1-METHYLINDOL-5-YL)UREA CAS_3277600 EU-0100255 L000536 N-(1-Methyl-1H-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea NCGC00015923-03 NSC_3277600 SB-204741 Tox21_500255 1-(1-methyl-1H-indol-5-yl)-3-(3-methylisothiazol-5-yl)urea AC1MLYNA B6708 HMS2231C03 LP00255 N-(1-Methyl-1H-indolyl-5-yl)-N''-(3-methyl-5-isothiazolyl) urea NCGC00015923-06 RTX-011453 SMR000326947 152239-46-8 BRD-K15391446-001-11-0 D04AZE J-008905 MolPort-003-959-484 NCGC00015923-01 NCGC00025129-03 SB 204741, >98% (HPLC) SR-01000075765-3 [ Show all ]
Inchi Key	USFUFHFQWXDVMH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H14N4OS/c1-9-7-13(20-17-9)16-14(19)15-11-3-4-12-10(8-11)5-6-18(12)2/h3-8H,1-2H3,(H2,15,16,19)
PubChem CID	3277600
ChEMBL	CHEMBL323356
IUPHAR	221
BindingDB	84991
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
344291	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
344289	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
344280	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
344281	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
344286	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
344278	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
556890	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
344277	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
344290	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
344276	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
344292	5-hydroxytryptamine receptor 2C	P34968	Htr2c	Mus musculus (Mouse)	459
344293	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
344295	5-hydroxytryptamine receptor 4	Q29006	HTR4	Sus scrofa (Pig)	137
344282	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
344287	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
344284	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
344283	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
344296	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
344279	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
344288	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460